MOTS-C

$200.00

Mitochondrial Research Compound

10 mg · Purity Exceeds 99% · For Research Only

A mitochondrial-derived peptide for laboratory research into AMPK signaling, mitochondrial-nuclear pathway characterization, and exercise-physiology signaling models. Designed for in-vitro and animal-model studies involving metabolic pathway analysis, NRF2-associated antioxidant signaling, and mitokine biology research.

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Overview
MOTS-C is a 16-amino-acid mitochondrial-derived peptide encoded by a short open reading frame within mitochondrial 12S rRNA. Research suggests that cellular stress and exercise can influence MOTS-C biology and that the peptide can interact with metabolic stress-response pathways, including folate-purine metabolism, AICAR accumulation, AMPK signaling, and adaptive nuclear gene expression. Most efficacy evidence remains preclinical, and no FDA-approved MOTS-C drug has been established.
Specification
Research identity: MOTS-C; mitochondrial ORF of the 12S rRNA type-c peptide
Sequence length: 16 amino-acid residues
Common sequence: MRWQEMGYIFYPRKLR
Approx. molecular mass: ~2,174.6 Da
Compound class: Mitochondrial-derived peptide
Physical form: Lyophilized research material; confirm presentation
Analytical controls: Identity, purity, net content, oxidation/degradation profile, and residual solvents
Potential Research Applications
Potential laboratory research domains include:
AMPK activation and cellular-energy-sensing studies
Folate-purine/AICAR metabolic pathway experiments
Skeletal-muscle glucose-utilization models
Exercise adaptation and metabolic-stress research
Mitochondrial-to-nuclear signaling and stress-response gene studies
Research limitation: These topics describe areas investigated in the literature. They do not establish safety, efficacy, or suitability for human or veterinary use.
FAQ
Where is MOTS-C encoded?
What is its commonly reported sequence?
Which pathway is frequently studied?
How mature is the evidence?
Is MOTS-C FDA approved?

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